Non-Surgical Treatment

Polynucleotides

Injectable biostimulators that rebuild collagen, restore elasticity and deeply hydrate

Treatment time: 30 to 45 minutes
Anaesthetic: Topical numbing cream
Downtime: Minimal; some redness or swelling possible
Sessions recommended: Course of 2 to 3 (discussed at consultation)

Overview

What are polynucleotides?

Polynucleotides are long-chain molecules derived from highly purified natural sources that act as powerful biostimulators in the skin. When injected, they work at a cellular level, stimulating fibroblasts to produce more collagen and elastin, improving hydration and antioxidant defence, and restoring the skin's structural integrity from within.

At Maison Restorative we use PhilArt Polynucleotides by Croma-Pharma, supported by over 70 years of research and more than 100 published studies. The treatment is suitable for all skin types and all ages: for younger patients it maintains and enriches skin health; for more mature patients it helps rejuvenate the face, neck, décolletage and hands by rebuilding elasticity and improving overall quality.

Polynucleotides also improve scarring by remodelling areas with high fibrous content, and they work particularly well alongside other aesthetic treatments such as laser, focused ultrasound and radiofrequency, enhancing and prolonging those results.

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Benefits

Why patients choose Polynucleotides

Stimulates collagen and elastin production for lasting improvement
Deeply hydrates by restoring the skin's moisture-retaining capacity
Improves skin texture, clarity and overall quality
Reduces fine lines and restores firmness and elasticity
Improves scarring by remodelling fibrous tissue
Enhances and prolongs results from other aesthetic treatments

Is it right for me?

Polynucleotides suit anyone looking to improve overall skin quality, restore lost elasticity, address fine lines or improve scarring, whether as a standalone treatment or alongside other procedures.

What to expect

What to expect from Polynucleotides

Step 1
Consultation
Your skin is assessed and your concerns discussed. Your practitioner explains whether polynucleotides are appropriate as a standalone treatment or as part of a combination programme.
Step 2
Treatment
Topical numbing cream is applied for comfort, then PhilArt is injected at carefully selected points. The session typically takes thirty to forty-five minutes.
Step 3
Aftercare and follow-up
Some mild redness or swelling is normal and settles within a day or two. Results develop over several weeks as collagen production increases; a follow-up session is usually recommended four to six weeks later.

Aftercare

Small raised bumps at each injection point are expected and usually settle within a few hours to a day, and mild redness, swelling or bruising is common. Apply a cold compress gently if the area feels swollen, and leave the treated skin alone rather than massaging it. Keep make-up off for around 12 hours, and use a gentle cleanser and moisturiser for the first day or two. Avoid strenuous exercise, saunas, steam rooms, hot baths and alcohol for 24 hours, and use a daily broad-spectrum SPF while the skin settles. Because this is a regenerative treatment rather than a filler, nothing dramatic happens immediately: the improvement in hydration, firmness and skin quality builds over the weeks following each session and across the course, so it is best judged once the full course is complete. Contact the clinic if swelling worsens after the first day or two, or if a lump persists beyond a couple of weeks.

FAQs

Frequently asked questions about Polynucleotides

What are polynucleotides made from?

PhilArt Polynucleotides are derived from highly purified natural sources. They are produced using a high purification technology that ensures safety, and are supported by over 70 years of research and more than 100 published studies.

How do polynucleotides differ from dermal fillers or Profhilo?

Dermal fillers add volume and physical structure; Profhilo spreads hyaluronic acid through the tissue as a hydrating bio-remodeller. Polynucleotides work differently, stimulating fibroblasts to produce the skin's own collagen and elastin. The focus is on improving skin quality and architecture rather than adding volume.

Which areas can be treated?

Polynucleotides are commonly used on the face, neck, décolletage and hands. They are also effective for improving the appearance of scars anywhere on the body.

How many sessions will I need?

A course of two to three sessions spaced four to six weeks apart is typical. Your practitioner will recommend the right number based on your skin and goals.

Can polynucleotides be combined with other treatments?

Yes, and this is one of their strengths. They complement and enhance results from laser, focused ultrasound, radiofrequency and injectables. Your practitioner will advise on the best sequencing.

How much do polynucleotide injections cost?

Pricing depends on the number of sessions agreed for you and is confirmed in writing at your consultation, with no obligation to proceed.

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